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5.4.3.2.1... Protein may not be required | 545 comments | Create New Account
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5.4.3.2.1... Protein may not be required
Authored by: hAckz0r on Friday, June 14 2013 @ 10:52 AM EDT
I don't recall whether they were actually producing the protein or just testing whether or not the attempt to copy a specific DNA strand (gene) succeeded; i.e., if the person has the gene.
That kind of test is much easier done with slicing and electrophoresis or a GeneChip(R) rather than the elaborate process of isolation and reverse polymerase. Its always cheaper to just tear something apart than to isolate and reassemble/recreate it.

I can imagine the latter process, in which case the protein isn't required.

If the DNA segment is a non-protein encoding segment then there is little point to isolating it for production purposes. There are some non-coding segments of DNA which are used mechanically during the transcription of neighbouring genes, or as binding sites for DNA methalation to deactivate a gene, but they have little intrinsic value in and of themselves. Remove them from the main DNA strand and you will merely affect the transcription of those neighbouring genes, but adding it in addition to the original copy, somewhere else, and it will not halt or double the output of anything meaningful. In most cases these non-transcribing DNA sequences are just termed Junk DNA, for obvious reasons.

---
The Investors IP Law: The future health of a Corporation is measured as the inverse of the number of IP lawsuits they are currently litigating.

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